Webinars from UC San Diego Center for Integrative Medicine about the latest talks in Integrative Medicine

Research Articles by topic

Osteopathic Manipulative Medicine

Meditation and Mindfulness

General Yoga

Yoga for Osteoarthritis

Yoga for Fibromyalgia

Yoga for Chronic Low Back Pain

Osteopathic Manipulative Medicine

A Comparison of Osteopathic Spinal Manipulation with Standard Care for Patients with Low Back Pain

Gunnar B.J. Andersson, M.D., Ph.D., Tracy Lucente, M.P.H., Andrew M. Davis, M.D., M.P.H., Robert E. Kappler, D.O., James A. Lipton, D.O., and Sue Leurgans, Ph.D.

  • A comparison of osteopathic spinal manipulation with standard care for patients with low back pain
  • Osteopathic manipulation and standard care had similar clinical outcomes. However, the patients in standard care protocol had a much greater use of medications (analgesics, anti-inflammatory agents, and muscle relaxants) and used more physical therapy.

http://www.nejm.org/doi/full/10.1056/NEJM199911043411903

Osteopathic manipulative medicine in the treatment of hypertension: an alternative, conventional approach.

Heart Disease 2003; July-Aug; 5(4):272-8 Spiegel et. Al

  • OMM might reduce sympathetic tone as effective supplemental treatment for hypertension in conjunction with long lasting treatment regimen.

http://www.ncbi.nlm.nih.gov/pubmed/12877760

 

Effects of Osteopathic Manipulative Treatment on Pediatric Patients With Asthma: A Randomized Controlled Trial

JAOA Vol 105 No 1 Jan 2005 Guiney et. Al

  • “Osteopathic manipulative (OM) techniques have been shown to increase vital capacity and rib cage mobility, improve diaphragmatic function, enhance the clearing of airway secretions, and possibly enhance autoimmune function”
  • OMT group showed statistically significant improvement of 7L to 9L / min peak expiratory flow rates. “This positive effect has been attributed to several factors, including a decrease in patients’ levels of anxiety, autonomic nervous system changes that relax the airways and smooth muscle tone, and, importantly, a mechanically improved chest wall motion.”

http://www.craniosuisse.ch/cm_data/Guiney_et_al_2005_J_Am_Osteopath_Assoc.pdf

 

Osteopathic manipulative treatment in conjunction with medication relieves pain associated with fibromyalgia syndrome: Results of a randomized clinical pilot project

JAOA Vol 102 No 6 June 2002 Russel et. Al

  • OMT combined with standard medical care was more effective than standard care alone based on measures of pain threshold, perceived pain, attitude toward treatment, activities of daily living, and perceived functional ability.
  • OMT group received one personalized treatment of 15-30 minutes per week, with modalities chosen at the discretion of the treating physician including myofascial release, muscle energy, soft tissue treatment, and craniosacral manipulation

http://www.bayviewmedical.org/wp-content/uploads/2016/01/omt-and-fm.pdf

 

Osteopathic Manipulative Treatment in Prenatal Care: A Retrospective Case Control Design Study

JAOA Vol 103 No 12 Dec 2003 Hollis King et. Al

  • Osteopathic treatment is consistently associated with lower rates of meconium stained amniotic fluid, pre-term deliveries, and use of forceps

http://omt4fp.tripod.com/Files/omt_preg_jaoa.pdf

 

A retrospective study of cranial strain patterns in patients with idiopathic Parkinson’s disease

JAOA Vol 99 No 2 Feb 1999 M R Wells, S Giantinoto, D D’Agate, RD Areman, EA Fazzini, D Dowling, and A Bosak

  • Standard osteopathic manipulative treatment acutely improves gait performance in patients with Parkinson’s
  • The data demonstrate that a single session of an OMT protocol has an immediate impact on Parkinsonian gait.
  • Treatment focuses on correcting unbalanced muscle tone to correct postural disturbances that contribute to tremor and other manifestations of disease.
  • “Possibly the greatest contribution of osteopathic manipulation to the treatment of neurodegenerative disease is the improvement of circulation and nutrition to the nervous tissue affected—more important, to the areas that have not yet been invaded by the disease process.”

https://www.researchgate.net/publication/11186126_A_retrospective_study_of_cranial_strain_patterns_in_patients_with_idiopathic_Parkinson%27s_disease

Meditation

The neural basis of the complex mental task of meditation: neurotransmitter and neurochemical considerations

Neuberg A, Iverson J. The neural basis of the complex mental task of meditation: neurotransmitter and neurochemical considerations.  Medical Hypotheses. 2003;61(2):282-291

  • Meditation activates neurochemical changes involving the endogenous opioid, GABA, nor- epinephrine, and serotonergic receptor systems.
  • Although there are still limitations in imaging, many patterns and activities of the brain can be understood with technological advances.

http://www.cogsci.ucsd.edu/~pineda/COGS175/readings/Newberg.pdf

 

 General Yoga

Psychophysiologic effects of Hatha Yoga on musculoskeletal and cardiopulmonary function: a literature review.

  • Sustained stretching activates opioid system, among other health benefits

Raub JA. Psychophysiologic effects of Hatha Yoga on musculoskeletal and cardiopulmonary function: a literature review. J Altern Complement Med. 2002;8:797–812.

http://www.ncbi.nlm.nih.gov/pubmed/12614533

 

Anterolateral Prefrontal Cortex Mediates the Analgesic Effect of Expected and Perceived Control over Pain

Wiech K, Kalisch R. Weiskopf N, et al. Anterolateral prefrontal cortex mediates the analgesic effect of expected and perceived control over pain. Journal of Neuroscience. 2006;26(44):11501-11509.

—  Beliefs about ability to control own pain affects experience of pain.

https://www.researchgate.net/publication/6716367_Anterolateral_Prefrontal_Cortex_Mediates_the_Analgesic_Effect_of_Expected_and_Perceived_Control_over_Pain

 

Exploring the therapeutic effects of yoga and its ability to increase quality of life.

Woodyard,C. Exploring the therapeutic effects of Yoga, and its ability to increase quality of life. Int J of Yoga. 2011 Jul-Dec; 4(2):49-54.

—  Yoga improves pain associated with: Chronic Low Back Pain, Fibromyalgia, Carpal Tunnel Syndrome, Headache, Arthritis

http://www.ncbi.nlm.nih.gov/pubmed/22022122

 

Yoga for Osteoarthritis:

—Iyengar Yoga for treatment of symptoms of Osteoarthritis

Kolasinski SL. Iyengar Yoga for treatment of symptoms of Osteoarthritis. J Altern Complement Med. 2005 Aug 11(4):689-93.Pilot study suggests Iyengar yoga offers potential reductions in pain and disability caused by knee OA.

  • Previously yoga-naive, obese patients >50 years of age

—The effect of Iyengar Yoga and strengthening exercises for people living with OA of the knee: a case series

Bukowski EL, et al. The effect of Iyengar Yoga and strengthening exercises for people living with OA of the knee: a case series. Int Q Community Health Educ. 2006-2007.26(2)287-305.

  • Case series demonstrated exercise in general and Iyengar Yoga in particular to improve pain and function in OA.

—Additional effects of Iyengar Yoga and EMG biofeedback in pain and functional disability in chronic unilateral knee OA

Nambi, GS, Shah AAS. Additional effects of Iyengar Yoga and EMG biofeedback in pain and functional disability in chronic unilateral knee OA. Int J Yoga. 2013 Jul-Dec; 6(2): 123–127

  • RCT showed significant improvement in pain and function in OA using Iyengar Yoga with EMG Biofeedback.

 

Yoga for fibromyalgia

Complementary and alternative exercises for fibromyalgia: a meta-analysis

Mist SD, Firestone KA, Jones KD. Complementary and alternative exercises for fibromyalgia: a meta-analysis. Jpain Res 2013;6:247-60.—

  • Evidence to date favors Yoga for decreasing pain and improving functioning.

—8 week yoga intervention is associated with improvements in pain; psychological functioning and mindfulness, and changes in cortisol levels in women with fibromyalgia

Curtis K, Osadchuk A, Katz J. An 8 week yoga intervention is associated with improvements in pain; psychological functioning and mindfulness, and changes in cortisol levels in women with fibromyalgia. J.Pain Res. 2011:4:189-201.

  • Pilot study demonstrated Hatha yoga class improved pain, reduced catastrophizing, decreased cortisol levels.

—Follow-up of Yoga of Awareness for Fibromyalgia: Results at 3 Months and Replication in the Wait-list group

Carson, JW, Carson KM, Jones, KD, Mist SD, Bennett SD. Follow-up of Yoga of Awareness for Fibromyalgia: Results at 3 Months and Replication in the Wait-list group. Clin J Pain, Vol 28(9)Nov/Dec 2012.

  • RCT re-demonstrated dose-dependent positive improvements in fibromyalgia symptoms using Yoga of Awareness.

—

Yoga for chronic low back pain

Comparing yoga, exercise, and a self-care book for chronic low back pain: a randomized, controlled trial

Sherman, KJ, Cherken DC. Comparing yoga, exercise, and a self-care book for chronic low back pain: a randomized, controlled trial.Ann Intern Med. 2005 Dec 20;143(12):849-56.—

  • Recent RCT demonstrated safety and efficacy of Viniyoga, a therapeutic yoga style, in treating CLBP that lasted greater than 3 months of follow-up.

—The impact of modified Hatha yoga on chronic low back pain: a pilot study

Galantino ML, Bzdewka TM, Eissler-Russo JL, Holbrook ML, Mogck EP, Geigle P, Farrar JT. The impact of modified Hatha yoga on chronic low back pain: a pilot study. AlternTherHealthMed. 2004 Mar-Apr;10(2):56-9

  • Pilot study demonstrated improvement in pain as well as depression and disability using Iyengar Yoga.

—Mediators of Yoga and Stretching for Chronic low back pain

Sherman KJ, Mediators of Yoga and Stretching for Chronic low back pain. Evid Based Complement Alternative Medicine 2013:2013

  • RCT evaluated mechanisms through which Yoga works (increased awareness and relaxation) as compared to stretching (routine and discipline).